Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis

BACKGROUND: Glioblastoma is refractory to conventional treatment, which is combined of surgery, chemotherapy and radiotherapy. Recent studies have shown that glioma initiating cells (GICs) contribute to tumorigenesis and radioresistance. Recently, other studies showed that the GICs use the autophagy...

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Detalles Bibliográficos
Autores principales: Ye, Hongxing, Chen, Mantao, Cao, Fei, Huang, Hongguang, Zhan, Renya, Zheng, Xiujue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029068/
https://www.ncbi.nlm.nih.gov/pubmed/27644442
http://dx.doi.org/10.1186/s12883-016-0700-6

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