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Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2

BACKGROUND: Pulmonary arterial hypertension (PAH) is a fatal disease characterized by impaired regulation of pulmonary artery vascular growth and remodeling. Aberrant expression of miR-17 has been shown to be involved in the pathogenesis of PAH, but its underlying molecular mechanism has not been el...

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Detalles Bibliográficos
Autores principales: Lu, Zheng, Li, Sujun, Zhao, Shunxin, Fa, Xianen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029176/
https://www.ncbi.nlm.nih.gov/pubmed/27640178
http://dx.doi.org/10.12659/MSM.900487

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