Cargando…

Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2

BACKGROUND: Pulmonary arterial hypertension (PAH) is a fatal disease characterized by impaired regulation of pulmonary artery vascular growth and remodeling. Aberrant expression of miR-17 has been shown to be involved in the pathogenesis of PAH, but its underlying molecular mechanism has not been el...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Zheng, Li, Sujun, Zhao, Shunxin, Fa, Xianen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2016
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029176/ https://www.ncbi.nlm.nih.gov/pubmed/27640178 http://dx.doi.org/10.12659/MSM.900487

Ejemplares similares

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression
por: Zhang, Liping, et al.
Publicado: (2020)

Long Noncoding RNA XR007793 Regulates Proliferation and Migration of Vascular Smooth Muscle Cell via Suppressing miR-23b
por: Wu, Ye-Xin, et al.
Publicado: (2018)

miR-188-3p Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Targeting Fibroblast Growth Factor 1 (FGF1)
por: Mi, Shaohua, et al.
Publicado: (2020)

miR-149-5p Inhibits Vascular Smooth Muscle Cells Proliferation, Invasion, and Migration by Targeting Histone Deacetylase 4 (HDAC4)
por: Zhang, Boya, et al.
Publicado: (2019)

miR-145-5p Inhibits Vascular Smooth Muscle Cells (VSMCs) Proliferation and Migration by Dysregulating the Transforming Growth Factor-β Signaling Cascade
por: Li, Li, et al.
Publicado: (2018)

miR-18a-5p Promotes Proliferation and Migration of Vascular Smooth Muscle Cells by Activating the AKT/Extracellular Regulated Protein Kinases (ERK) Signaling Pathway
por: Zhang, Yuanheng, et al.
Publicado: (2020)

MicroRNA-214-3p Regulates Hypoxia-Mediated Pulmonary Artery Smooth Muscle Cell Proliferation and Migration by Targeting ARHGEF12
por: Xing, Xi-Qian, et al.
Publicado: (2019)

Upregulation of Long Noncoding RNA GAS5 Inhibits Lung Cancer Cell Proliferation and Metastasis via miR-205/PTEN Axis
por: Dong, Lizhen, et al.
Publicado: (2019)

miR-483-5p Targets MKNK1 to Suppress Wilms’ Tumor Cell Proliferation and Apoptosis In Vitro and In Vivo
por: Liu, Kai, et al.
Publicado: (2019)

miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway
por: Yu, Jinzhong, et al.
Publicado: (2017)

Dexmedetomidine Regulates Proliferation, Apoptosis, Migration, and Invasion in Ovarian Cancer Cells via MiR-155-HIF-1α Axis
por: Zheng, Lihong, et al.
Publicado: (2019)

A Regulatory Axis of circ_0008193/miR-1180-3p/TRIM62 Suppresses Proliferation, Migration, Invasion, and Warburg Effect in Lung Adenocarcinoma Cells Under Hypoxia
por: Chen, Minbiao, et al.
Publicado: (2020)

miR-206 Inhibits Cell Proliferation and Extracellular Matrix Accumulation by Targeting Hypoxia-Inducible Factor 1-alpha (HIF-1α) in Mesangial Cells Treated with High Glucose
por: Cao, Yanchao, et al.
Publicado: (2019)

Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression
por: Wu, Cuiping, et al.
Publicado: (2016)

Evaluation of Hypoxia on the Expression of miR-646/IGF-1 Signaling in Human Periodontal Ligament Cells (hPDLCs)
por: Yang, Jun, et al.
Publicado: (2018)

miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells
por: Song, Lijie, et al.
Publicado: (2017)

MiR-769 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Targeting HEY1
por: Han, Chao, et al.
Publicado: (2018)

miR-652 Promotes Proliferation and Migration of Uveal Melanoma Cells by Targeting HOXA9
por: Xia, Zhaoxia, et al.
Publicado: (2019)

Long Non-coding RNA Zinc Finger Antisense 1 (ZFAS1) Regulates Proliferation, Migration, Invasion, and Apoptosis by Targeting MiR-7-5p in Colorectal Cancer
por: Mo, Dianjun, et al.
Publicado: (2019)

miR-200bc/429 Inhibits Osteosarcoma Cell Proliferation and Invasion by Targeting PMP22
por: Li, Xiaodong, et al.
Publicado: (2017)

Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2
por: Wang, Guanghui, et al.
Publicado: (2019)

miR-143 Induces the Apoptosis of Prostate Cancer LNCap Cells by Suppressing Bcl-2 Expression
por: Ma, Zhiwei, et al.
Publicado: (2017)

Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181
por: Gong, Jiangjiang, et al.
Publicado: (2017)

Plasma miR-15b-5p, miR-338-5p, and miR-764 as Biomarkers for Hepatocellular Carcinoma
por: Chen, Yi, et al.
Publicado: (2015)

Upregulated hsa_circ_0004458 Contributes to Progression of Papillary Thyroid Carcinoma by Inhibition of miR-885-5p and Activation of RAC1
por: Jin, Xiaoyan, et al.
Publicado: (2018)

Downregulation of lncRNA X Inactive Specific Transcript (XIST) Suppresses Cell Proliferation and Enhances Radiosensitivity by Upregulating mir-29c in Nasopharyngeal Carcinoma Cells
por: Han, Qian, et al.
Publicado: (2017)

Long Noncoding RNA HOTTIP Promotes Nasopharyngeal Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-4301
por: Shen, Meiqin, et al.
Publicado: (2019)

miR-126 Suppresses Invasion and Migration of Malignant Glioma by Targeting Mature T Cell Proliferation 1 (MTCP1)
por: Han, Liangbo, et al.
Publicado: (2018)

miR-325-3p Overexpression Inhibits Proliferation and Metastasis of Bladder Cancer Cells by Regulating MT3
por: Sun, Shaopeng, et al.
Publicado: (2020)

Circular RNA-0001283 Suppresses Breast Cancer Proliferation and Invasion via MiR-187/HIPK3 Axis
por: Hu, Ying, et al.
Publicado: (2020)

Aberrant Expression of microRNA-9 Contributes to Development of Intracranial Aneurysm by Suppressing Proliferation and Reducing Contractility of Smooth Muscle Cells
por: Luo, Jing, et al.
Publicado: (2016)

Expression of Long Noncoding RNA LIPCAR Promotes Cell Proliferation, Cell Migration, and Change in Phenotype of Vascular Smooth Muscle Cells
por: Wang, Xiaoyan, et al.
Publicado: (2019)

Ghrelin Alleviates Angiotensin II-Induced H9c2 Apoptosis: Impact of the miR-208 Family
por: Wang, Xiaotong, et al.
Publicado: (2018)

miR-512-3p Overcomes Resistance to Cisplatin in Retinoblastoma by Promoting Apoptosis Induced by Endoplasmic Reticulum Stress
por: Kong, Miao, et al.
Publicado: (2020)

The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro
por: Zhang, Shuang-li, et al.
Publicado: (2018)

Circular RNA CircMTO1 Inhibits Proliferation of Glioblastoma Cells via miR-92/WWOX Signaling Pathway
por: Zhang, Xuewen, et al.
Publicado: (2019)

Cyclic Stretch Promotes Proliferation and Contraction of Human Bladder Smooth Muscle Cells by Cajal-Mediated c-kit Expression in Interstitial Cells
por: Pingyu, Zhu, et al.
Publicado: (2019)

Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells
por: Sang, Hai-yan, et al.
Publicado: (2016)

Suppression of miR-21 Expression Inhibits Cell Proliferation and Migration of Liver Cancer Cells by Targeting Phosphatase and Tensin Homolog (PTEN)
por: Liu, Haiwei, et al.
Publicado: (2018)

Long Non-Coding RNA (LncRNA) UFC1/miR-34a Contributes to Proliferation and Migration in Breast Cancer
por: Xie, Ruilian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dqfhtjtf4vds3ro1ta8k425675