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Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study

BACKGROUND: Cutaneous leishmaniasis (CL) usually occurs in areas with hot and dry climate. In India, the desert areas of Rajasthan, Gujarat, and the plains of Northwestern frontier are endemic for this disorder. AIMS AND OBJECTIVES: The present study was aimed to describe clinicoepidemiological prof...

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Autores principales: Balai, Manisha, Gupta, Lalit Kumar, Khare, Ashok Kumar, Srivastava, Ankita, Mittal, Asit, Singh, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029237/
https://www.ncbi.nlm.nih.gov/pubmed/27688441
http://dx.doi.org/10.4103/0019-5154.190117
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author Balai, Manisha
Gupta, Lalit Kumar
Khare, Ashok Kumar
Srivastava, Ankita
Mittal, Asit
Singh, Ajit
author_facet Balai, Manisha
Gupta, Lalit Kumar
Khare, Ashok Kumar
Srivastava, Ankita
Mittal, Asit
Singh, Ajit
author_sort Balai, Manisha
collection PubMed
description BACKGROUND: Cutaneous leishmaniasis (CL) usually occurs in areas with hot and dry climate. In India, the desert areas of Rajasthan, Gujarat, and the plains of Northwestern frontier are endemic for this disorder. AIMS AND OBJECTIVES: The present study was aimed to describe clinicoepidemiological profile of the cases of CL from South Rajasthan, which is a nonendemic area of Rajasthan. MATERIALS AND METHODS: During a period of 4 years (2010–2014), a total of 23 patients with CL were diagnosed. All the suspected cases of CL were interrogated in detail regarding visit to areas where CL is known to occur. This was followed by clinical examination, relevant investigations, and treatment. All except one patient were treated with azole antifungals. In one patient, CO(2) laser ablation was done. RESULTS: There were 12 (52.17%) males and 11 (47.83%) females with age ranging from 3 to 72 years. Duration of disease ranged from 7 days to 10 months. Face (15; 65.22%) and extremities (12; 52.17%) were involved in majority of the patients. Common morphologies were noduloulcerative lesions and crusted plaques. Tissue smear for Leishmania donovani bodies was positive in all except one patient. CONCLUSION: The present report highlights occurrence of CL in nonendemic area. Further epidemiological studies are required for identification of vector and strain of Leishmania involved.
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spelling pubmed-50292372016-09-29 Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study Balai, Manisha Gupta, Lalit Kumar Khare, Ashok Kumar Srivastava, Ankita Mittal, Asit Singh, Ajit Indian J Dermatol Original Article BACKGROUND: Cutaneous leishmaniasis (CL) usually occurs in areas with hot and dry climate. In India, the desert areas of Rajasthan, Gujarat, and the plains of Northwestern frontier are endemic for this disorder. AIMS AND OBJECTIVES: The present study was aimed to describe clinicoepidemiological profile of the cases of CL from South Rajasthan, which is a nonendemic area of Rajasthan. MATERIALS AND METHODS: During a period of 4 years (2010–2014), a total of 23 patients with CL were diagnosed. All the suspected cases of CL were interrogated in detail regarding visit to areas where CL is known to occur. This was followed by clinical examination, relevant investigations, and treatment. All except one patient were treated with azole antifungals. In one patient, CO(2) laser ablation was done. RESULTS: There were 12 (52.17%) males and 11 (47.83%) females with age ranging from 3 to 72 years. Duration of disease ranged from 7 days to 10 months. Face (15; 65.22%) and extremities (12; 52.17%) were involved in majority of the patients. Common morphologies were noduloulcerative lesions and crusted plaques. Tissue smear for Leishmania donovani bodies was positive in all except one patient. CONCLUSION: The present report highlights occurrence of CL in nonendemic area. Further epidemiological studies are required for identification of vector and strain of Leishmania involved. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5029237/ /pubmed/27688441 http://dx.doi.org/10.4103/0019-5154.190117 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Balai, Manisha
Gupta, Lalit Kumar
Khare, Ashok Kumar
Srivastava, Ankita
Mittal, Asit
Singh, Ajit
Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title_full Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title_fullStr Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title_full_unstemmed Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title_short Cutaneous Leishmaniasis in a Nonendemic Area of South Rajasthan: A Prospective Study
title_sort cutaneous leishmaniasis in a nonendemic area of south rajasthan: a prospective study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029237/
https://www.ncbi.nlm.nih.gov/pubmed/27688441
http://dx.doi.org/10.4103/0019-5154.190117
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