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mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice

The mammalian target of rapamycin (Mtor) gene encodes a serine/threonine kinase that acts as a master regulator of processes as diverse as cell growth, protein synthesis, cytoskeleton reorganization, and cell survival. In the testis, physiological roles for Mtor have been proposed in perinatal Serto...

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Detalles Bibliográficos
Autores principales: Boyer, Alexandre, Girard, Meggie, Thimmanahalli, Dayananda S., Levasseur, Adrien, Céleste, Christophe, Paquet, Marilène, Duggavathi, Rajesha, Boerboom, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029431/
https://www.ncbi.nlm.nih.gov/pubmed/27281705
http://dx.doi.org/10.1095/biolreprod.115.138016