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Identification of new branch points and unconventional introns in Saccharomyces cerevisiae

Spliced messages constitute one-fourth of expressed mRNAs in the yeast Saccharomyces cerevisiae, and most mRNAs in metazoans. Splicing requires 5′ splice site (5′SS), branch point (BP), and 3′ splice site (3′SS) elements, but the role of the BP in splicing control is poorly understood because BP ide...

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Detalles Bibliográficos
Autores principales: Gould, Genevieve M., Paggi, Joseph M., Guo, Yuchun, Phizicky, David V., Zinshteyn, Boris, Wang, Eric T., Gilbert, Wendy V., Gifford, David K., Burge, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029451/
https://www.ncbi.nlm.nih.gov/pubmed/27473169
http://dx.doi.org/10.1261/rna.057216.116