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An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells

Estrogen receptor α (ERα) is an important biomarker of breast cancer severity and a common therapeutic target. In response to estrogen, ERα stimulates a dynamic transcriptional program including both coding and noncoding RNAs. We generate a fine-scale map of expression dynamics by performing a tempo...

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Detalles Bibliográficos
Autores principales: Baran-Gale, Jeanette, Purvis, Jeremy E., Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029456/
https://www.ncbi.nlm.nih.gov/pubmed/27539783
http://dx.doi.org/10.1261/rna.056895.116

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