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Trophoblast Major Histocompatibility Complex Class I Expression Is Associated with Immune-Mediated Rejection of Bovine Fetuses Produced by Cloning

Trophoblast cells from bovine somatic cell nuclear transfer (SCNT) conceptuses express major histocompatibility complex class I (MHC-I) proteins early in gestation, and this may be one cause of the significant first-trimester embryonic mortality observed in these pregnancies. MHC-I homozygous-compat...

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Detalles Bibliográficos
Autores principales: Rutigliano, Heloisa M., Thomas, Aaron J., Wilhelm, Amanda, Sessions, Benjamin R., Hicks, Brady A., Schlafer, Donald H., White, Kenneth L., Davies, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029473/
https://www.ncbi.nlm.nih.gov/pubmed/27385783
http://dx.doi.org/10.1095/biolreprod.115.136523