Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes

The splicing factor SF3B1 is the most frequently mutated gene in myelodysplastic syndromes (MDS), and is strongly associated with the presence of ring sideroblasts (RS). We have performed a systematic analysis of cryptic splicing abnormalities from RNA sequencing data on hematopoietic stem cells (HS...

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Detalles Bibliográficos
Autores principales: Dolatshad, H, Pellagatti, A, Liberante, F G, Llorian, M, Repapi, E, Steeples, V, Roy, S, Scifo, L, Armstrong, R N, Shaw, J, Yip, B H, Killick, S, Kušec, R, Taylor, S, Mills, K I, Savage, K I, Smith, C W J, Boultwood, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029572/
https://www.ncbi.nlm.nih.gov/pubmed/27211273
http://dx.doi.org/10.1038/leu.2016.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029572/
https://www.ncbi.nlm.nih.gov/pubmed/27211273
http://dx.doi.org/10.1038/leu.2016.149

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