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The emerging role of FTY720 (Fingolimod) in cancer treatment
FTY720 (Fingolimod) is a clinically approved immunomodulating therapy for multiple sclerosis that sequesters T-cells to lymph nodes through functional antagonism of sphingosine-1-phosphate 1 receptor. FTY720 also demonstrates a proven efficacy in multiple in vitro and in vivo cancer models, suggesti...
Autores principales: | White, Christopher, Alshaker, Heba, Cooper, Colin, Winkler, Matthias, Pchejetski, Dmitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029614/ https://www.ncbi.nlm.nih.gov/pubmed/27036015 http://dx.doi.org/10.18632/oncotarget.7145 |
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