Depletion of FAP(+) cells reduces immunosuppressive cells and improves metabolism and functions CD8(+)T cells within tumors

The tumor stroma, which is essential to support growth and metastasis of malignant cells, provides targets for active immunotherapy of cancer. Previous studies have shown that depleting fibroblast activation protein (FAP)-expressing stromal cells reduces tumor progression and concomitantly increases...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Ertl, Hildegund C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029626/
https://www.ncbi.nlm.nih.gov/pubmed/26943036
http://dx.doi.org/10.18632/oncotarget.7818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029626/
https://www.ncbi.nlm.nih.gov/pubmed/26943036
http://dx.doi.org/10.18632/oncotarget.7818

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