Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models

To evaluate the significance of interleukin 4 (IL-4) in tumor development, we compared B16F10 melanoma growth in IL-4-overespressing transgenic mice (IL-4 mice) and non-transgenic mice. In IL-4 mice, reduced tumor volume and weight were observed when compared with those of non-transgenic mice. Signi...

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Detalles Bibliográficos
Autores principales: Lee, Hye Lim, Park, Mi Hee, Song, Ju Kyoung, Jung, Yu Yeon, Kim, Youngsoo, Kim, Kyung Bo, Hwang, Dae Yeon, Yoon, Do Young, Song, Min Jong, Han, Sang Bae, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029637/
https://www.ncbi.nlm.nih.gov/pubmed/26993600
http://dx.doi.org/10.18632/oncotarget.8111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029637/
https://www.ncbi.nlm.nih.gov/pubmed/26993600
http://dx.doi.org/10.18632/oncotarget.8111

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