Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression

The saponin fraction of Aesculus chinensis Bunge fruits (SFAC) could inhibit the invasion and migration of MDA-MB-231 cells. Among which, escin Ia showed more potent inhibition of the invasion than other five main saponin constituents. It selectively reduced the expression of LOXL2 mRNA and promoted...

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Detalles Bibliográficos
Autores principales: Wang, Yuhui, Xu, Xiaotian, Zhao, Peng, Tong, Bei, Wei, Zhifeng, Dai, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029656/
https://www.ncbi.nlm.nih.gov/pubmed/27008697
http://dx.doi.org/10.18632/oncotarget.8152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029656/
https://www.ncbi.nlm.nih.gov/pubmed/27008697
http://dx.doi.org/10.18632/oncotarget.8152

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