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Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression

The saponin fraction of Aesculus chinensis Bunge fruits (SFAC) could inhibit the invasion and migration of MDA-MB-231 cells. Among which, escin Ia showed more potent inhibition of the invasion than other five main saponin constituents. It selectively reduced the expression of LOXL2 mRNA and promoted...

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Detalles Bibliográficos
Autores principales:	Wang, Yuhui, Xu, Xiaotian, Zhao, Peng, Tong, Bei, Wei, Zhifeng, Dai, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029656/ https://www.ncbi.nlm.nih.gov/pubmed/27008697 http://dx.doi.org/10.18632/oncotarget.8152

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