The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners

The DEK oncogene is overexpressed in various cancers and overexpression of DEK correlates with poor clinical outcome. Vascular endothelial growth factor (VEGF) is the most important regulator of tumor angiogenesis, a process essential for tumor growth and metastasis. However, whether DEK enhances tu...

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Detalles Bibliográficos
Autores principales: Zhang, Yanan, Liu, Jie, Wang, Shibin, Luo, Xiaoli, Li, Yang, Lv, Zhaohui, Zhu, Jie, Lin, Jing, Ding, Lihua, Ye, Qinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029660/
https://www.ncbi.nlm.nih.gov/pubmed/26988756
http://dx.doi.org/10.18632/oncotarget.8060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029660/
https://www.ncbi.nlm.nih.gov/pubmed/26988756
http://dx.doi.org/10.18632/oncotarget.8060

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