Rnf25/AO7 positively regulates wnt signaling via disrupting Nkd1-Axin inhibitory complex independent of its ubiquitin ligase activity

Wnt signaling components have been shown to control key events in embryogenesis and to maintain tissue homeostasis in the adult. Nkd1/2 and Axin1/2 protein families are required for feedback regulation of Wnt signaling. The mechanisms by which Nkd1 and Nkd2 exhibit significant differences in signal...

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Detalles Bibliográficos
Autores principales: Gao, Rui, Ma, Lin-Qiang, Du, Xiaogang, Zhang, Ting-Ting, Zhao, Liang, Liu, Luhong, Liu, Jing-Crystal, Guo, Fengjin, Cheng, Zhi, Huang, Huizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029668/
https://www.ncbi.nlm.nih.gov/pubmed/27007149
http://dx.doi.org/10.18632/oncotarget.8126

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