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C-terminal truncated hepatitis B virus X protein promotes hepatocellular carcinogenesis through induction of cancer and stem cell-like properties

Tumor relapse after chemotherapy typifies hepatocellular carcinoma (HCC) and is believed to be attributable to residual cancer stem cells (CSCs) that survive initial treatment. Chronic infection with hepatitis B virus (HBV) has long been linked to the development of HCC. Upon infection, random HBV g...

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Detalles Bibliográficos
Autores principales: Ng, Kai-Yu, Chai, Stella, Tong, Man, Guan, Xin-Yuan, Lin, Chi-Ho, Ching, Yick-Pang, Xie, Dan, Cheng, Alfred Sze-Lok, Ma, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029680/
https://www.ncbi.nlm.nih.gov/pubmed/27006468
http://dx.doi.org/10.18632/oncotarget.8209

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