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Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis

Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60–80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare, recurrent/metastatic disease accounts for nearly all related deaths. An in vivo pre-clinical model for these invasive cancers is necessary for tes...

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Detalles Bibliográficos
Autores principales: Vermeer, Daniel W., Coppock, Joseph D., Zeng, Erliang, Lee, Kimberly M., Spanos, William C., Onken, Michael D., Uppaluri, Ravindra, Lee, John H., Vermeer, Paola D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029694/
https://www.ncbi.nlm.nih.gov/pubmed/27013584
http://dx.doi.org/10.18632/oncotarget.8254