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Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy
Several clinical trials indicate that concurrent administration of tyrosine kinase inhibitors (TKIs, such as gefitinib or erlotinib) with chemotherapy agents fails to improve overall survival in advanced non-small cell lung cancer (NSCLC) patients. However, the precise mechanisms underlying the anta...
Autores principales: | Li, Xiao-Qiu, Liu, Jia-Tao, Fan, Lu-Lu, Liu, Yu, Cheng, Liang, Wang, Fang, Yu, Han-Qing, Gao, Jian, Wei, Wei, Wang, Hua, Sun, Guo-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029725/ https://www.ncbi.nlm.nih.gov/pubmed/27029054 http://dx.doi.org/10.18632/oncotarget.8358 |
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