Epithelial-to-mesenchymal transition leads to loss of EpCAM and different physical properties in circulating tumor cells from metastatic breast cancer

The dissemination of circulating tumor cells (CTCs) requires the Epithelial-to-Mesenchymal transition (EMT), in which cells lose their epithelial characteristics and acquire more mesenchymal-like phenotypes. Current isolation of CTCs relies on affinity-based approaches reliant on the expression of E...

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Detalles Bibliográficos
Autores principales: Hyun, Kyung-A, Koo, Gi-Bang, Han, Hyunju, Sohn, Joohyuk, Choi, Wonshik, Kim, Seung-Il, Jung, Hyo-Il, Kim, You-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029733/
https://www.ncbi.nlm.nih.gov/pubmed/27013581
http://dx.doi.org/10.18632/oncotarget.8250

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