Mechanical stretch‐induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection

Thoracic aortic aneurysm/dissection (TAAD) is characterized by excessive smooth muscle cell (SMC) loss, extracellular matrix (ECM) degradation and inflammation. In response to certain stimuli, endoplasmic reticulum (ER) stress is activated and regulates apoptosis and inflammation. Excessive apoptosi...

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Detalles Bibliográficos
Autores principales: Jia, Li‐Xin, Zhang, Wen‐Mei, Zhang, Hong‐Jia, Li, Tao‐Tao, Wang, Yue‐Li, Qin, Yan‐Wen, Gu, Hong, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029755/
https://www.ncbi.nlm.nih.gov/pubmed/25788370
http://dx.doi.org/10.1002/path.4534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029755/
https://www.ncbi.nlm.nih.gov/pubmed/25788370
http://dx.doi.org/10.1002/path.4534

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