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Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials
OBJECTIVE: A number of promising experimental therapies for Duchenne muscular dystrophy (DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation-dependent functional tests to assess outcome. Quantitative muscle magnetic resonance imaging (MRI) could offer a valuable alte...
Autores principales: | Ricotti, Valeria, Evans, Matthew R. B., Sinclair, Christopher D. J., Butler, Jordan W., Ridout, Deborah A., Hogrel, Jean-Yves, Emira, Ahmed, Morrow, Jasper M., Reilly, Mary M., Hanna, Michael G., Janiczek, Robert L., Matthews, Paul M., Yousry, Tarek A., Muntoni, Francesco, Thornton, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029878/ https://www.ncbi.nlm.nih.gov/pubmed/27649492 http://dx.doi.org/10.1371/journal.pone.0162542 |
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