Association between P16(INK4a) Promoter Methylation and Ovarian Cancer: A Meta-Analysis of 12 Published Studies

BACKGROUND: Ovarian cancer is the primary cause of death in women diagnosed with gynecological malignancies worldwide. Absence of early symptoms prevents prompt diagnosis or successful therapeutic intervention. P16(INK4a) is a well-known tumor suppressor gene (TSG). Aberrant methylation of TSG promo...

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Detalles Bibliográficos
Autores principales: Xiao, Xiyue, Cai, Fucheng, Niu, Xun, Shi, Hao, Zhong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029926/
https://www.ncbi.nlm.nih.gov/pubmed/27648827
http://dx.doi.org/10.1371/journal.pone.0163257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029926/
https://www.ncbi.nlm.nih.gov/pubmed/27648827
http://dx.doi.org/10.1371/journal.pone.0163257

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