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Association between P16(INK4a) Promoter Methylation and Ovarian Cancer: A Meta-Analysis of 12 Published Studies
BACKGROUND: Ovarian cancer is the primary cause of death in women diagnosed with gynecological malignancies worldwide. Absence of early symptoms prevents prompt diagnosis or successful therapeutic intervention. P16(INK4a) is a well-known tumor suppressor gene (TSG). Aberrant methylation of TSG promo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029926/ https://www.ncbi.nlm.nih.gov/pubmed/27648827 http://dx.doi.org/10.1371/journal.pone.0163257 |