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SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

F-box proteins share the F-box domain to connect substrates of E3 SCF ubiquitin RING ligases through the adaptor Skp1/A to Cul1/A scaffolds. F-box protein Fbx15 is part of the general stress response of the human pathogenic mold Aspergillus fumigatus. Oxidative stress induces a transient peak of fbx...

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Detalles Bibliográficos
Autores principales: Jöhnk, Bastian, Bayram, Özgür, Abelmann, Anja, Heinekamp, Thorsten, Mattern, Derek J., Brakhage, Axel A., Jacobsen, Ilse D., Valerius, Oliver, Braus, Gerhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029927/
https://www.ncbi.nlm.nih.gov/pubmed/27649508
http://dx.doi.org/10.1371/journal.ppat.1005899