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Identification of Claudin 1 Transcript Variants in Human Invasive Breast Cancer

BACKGROUND: The claudin 1 tight junction protein, solely responsible for the barrier function of epithelial cells, is frequently down regulated in invasive human breast cancer. The underlying mechanism is largely unknown, and no obvious mutations in the claudin 1 gene (CLDN1) have been identified to...

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Detalles Bibliográficos
Autores principales: Blanchard, Anne A., Zelinski, Teresa, Xie, Jiuyong, Cooper, Steven, Penner, Carla, Leygue, Etienne, Myal, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029943/
https://www.ncbi.nlm.nih.gov/pubmed/27649506
http://dx.doi.org/10.1371/journal.pone.0163387