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Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis

Mitochondrial DNA (mtDNA) depletion occurs frequently in many diseases including cancer. The present study was designed in order to examine the hypothesis that mtDNA-depleted cells are resistant to apoptosis and to explore the possible mechanisms responsible for this effect. Parental human osteosarc...

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Detalles Bibliográficos
Autores principales:	Chen, Hulin, Wang, Junling, Liu, Zhongrong, Yang, Huilan, Zhu, Yingjie, Zhao, Minling, Liu, Yan, Yan, Miaomiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029958/ https://www.ncbi.nlm.nih.gov/pubmed/27499009 http://dx.doi.org/10.3892/ijmm.2016.2697

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