Cargando…

Structural basis of laminin binding to the LARGE glycans on dystroglycan

Dystroglycan is a highly glycosylated extracellular matrix receptor with essential functions in skeletal muscle and the nervous system. Reduced matrix binding by α-dystroglycan (α-DG) due to perturbed glycosylation is a pathological feature of several forms of muscular dystrophy. Like-acetylglucosam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Briggs, David C., Yoshida-Moriguchi, Takako, Zheng, Tianqing, Venzke, David, Anderson, Mary, Strazzulli, Andrea, Moracci, Marco, Yu, Liping, Hohenester, Erhard, Campbell, Kevin P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030134/ https://www.ncbi.nlm.nih.gov/pubmed/27526028 http://dx.doi.org/10.1038/nchembio.2146

Ejemplares similares

Loss of α-Dystroglycan Laminin Binding in Epithelium-derived Cancers Is Caused by Silencing of LARGE
por: de Bernabé, Daniel Beltrán-Valero, et al.
Publicado: (2009)

Laminin: the crux of basement membrane assembly
por: Sasaki, Takako, et al.
Publicado: (2004)

Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane
por: Yoshida-Moriguchi, Takako, et al.
Publicado: (2015)

Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111
por: Pulido, David, et al.
Publicado: (2017)

Structural biology of laminins
por: Hohenester, Erhard
Publicado: (2019)

Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma
por: Beltrán, Daniel, et al.
Publicado: (2019)

Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2
por: Inamori, Kei-ichiro, et al.
Publicado: (2013)

N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy
por: Okuma, Hidehiko, et al.
Publicado: (2023)

Laminins in basement membrane assembly
por: Hohenester, Erhard, et al.
Publicado: (2013)

Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1
por: Briggs, David C., et al.
Publicado: (2018)

Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domains
por: Pulido, David, et al.
Publicado: (2017)

High degree of conservation of the enzymes synthesizing the laminin-binding glycoepitope of α-dystroglycan
por: Bigotti, Maria Giulia, et al.
Publicado: (2021)

biAb Mediated Restoration of the Linkage between Dystroglycan and Laminin-211 as a Therapeutic Approach for α-Dystroglycanopathies
por: Gumlaw, Nathan, et al.
Publicado: (2020)

Laminin Network Formation Studied by Reconstitution of Ternary Nodes in Solution
por: Purvis, Alan, et al.
Publicado: (2012)

Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy
por: Kanagawa, Motoi, et al.
Publicado: (2009)

LARGE Expression Augments the Glycosylation of Glycoproteins in Addition to α-Dystroglycan Conferring Laminin Binding
por: Zhang, Zhen, et al.
Publicado: (2011)

Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins
por: Ruan, Jingsong, et al.
Publicado: (2022)

Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function
por: Sheikh, M. Osman, et al.
Publicado: (2022)

ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome
por: Willer, Tobias, et al.
Publicado: (2012)

Crystal Structure of the LG1-3 Region of the Laminin α2 Chain
por: Carafoli, Federico, et al.
Publicado: (2009)

POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan
por: Walimbe, Ameya S, et al.
Publicado: (2020)

Determinants of laminin polymerization revealed by the structure of the α5 chain amino-terminal region
por: Hussain, Sadaf-Ahmahni, et al.
Publicado: (2011)

Characterization of dystroglycan binding in adhesion of human induced pluripotent stem cells to laminin-511 E8 fragment
por: Sugawara, Yumika, et al.
Publicado: (2019)

Linker molecules between laminins and dystroglycan ameliorate laminin-α2–deficient muscular dystrophy at all disease stages
por: Meinen, Sarina, et al.
Publicado: (2007)

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation
por: Willer, Tobias, et al.
Publicado: (2014)

Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin β1 and γ1 Chains
por: Carafoli, Federico, et al.
Publicado: (2012)

Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation
por: de Greef, Jessica C., et al.
Publicado: (2019)

Laminin-induced Clustering of Dystroglycan on Embryonic Muscle Cells: Comparison with Agrin-induced Clustering
por: Cohen, Monroe W., et al.
Publicado: (1997)

The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition
por: Praissman, Jeremy L, et al.
Publicado: (2016)

α-Dystroglycan Is a Laminin Receptor Involved in Extracellular Matrix Assembly on Myotubes and Muscle Cell Viability
por: Montanaro, Federica, et al.
Publicado: (1999)

The Molecular Basis and Biologic Significance of the β-Dystroglycan-Emerin Interaction
por: Gómez-Monsivais, Wendy Lilián, et al.
Publicado: (2020)

An atypical expression of core α-Dystroglycan and Laminin-α2 in skin fibroblasts of patients with congenital muscular dystrophies
por: Sabry, Sahar, et al.
Publicado: (2023)

The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function
por: Yatsenko, AS, et al.
Publicado: (2009)

M. leprae interacts with the human epidermal keratinocytes, neonatal (HEKn) via the binding of laminin-5 with α-dystroglycan, integrin-β1, or -β4
por: Jin, Song-Hyo, et al.
Publicado: (2019)

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan
por: Yagi, Hirokazu, et al.
Publicado: (2013)

A High Throughput Screen Identifies Chemical Modulators of the Laminin-Induced Clustering of Dystroglycan and Aquaporin-4 in Primary Astrocytes
por: Noël, Geoffroy, et al.
Publicado: (2011)

Large Induces Functional Glycans in an O-Mannosylation Dependent Manner and Targets GlcNAc Terminals on Alpha-Dystroglycan
por: Hu, Yihong, et al.
Publicado: (2011)

Lassa Fever Virus Binds Matriglycan—A Polymer of Alternating Xylose and Glucuronate—On α-Dystroglycan
por: Joseph, Soumya, et al.
Publicado: (2021)

A stoichiometric complex of neurexins and dystroglycan in brain
por: Sugita, Shuzo, et al.
Publicado: (2001)

Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1–4
por: Paracuellos, Patricia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mijdth8qkvesceg2abg070nl7a