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FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions
Guanine-nucleotide dissociation inhibitors (GDI) are negative regulators of Rho family GTPases that sequester the GTPases away from the membrane. Here we ask how GDI-Cdc42 interaction regulates localized Cdc42 activation for cell motility. The sensitivity of cells to overexpression of Rho family pat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030135/ https://www.ncbi.nlm.nih.gov/pubmed/27501396 http://dx.doi.org/10.1038/nchembio.2145 |