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Preparation and Characterization of Loperamide-Loaded Dynasan 114 Solid Lipid Nanoparticles for Increased Oral Absorption In the Treatment of Diarrhea

The aim of the project was to assemble two optimum solid lipid nanoparticle (SLN) formulations for oral delivery of loperamide (LPM) to treat different types of diarrhea, and to evaluate their release profiles in vitro and pharmacokinetic properties in vivo. In this work, glyceryl trimyristate (Dyna...

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Detalles Bibliográficos
Autores principales:	Wei, Lili, Yang, Yunfang, Shi, Kun, Wu, Jun, Zhao, Wei, Mo, Jingxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030211/ https://www.ncbi.nlm.nih.gov/pubmed/27708583 http://dx.doi.org/10.3389/fphar.2016.00332

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