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Patterns of Co-Occurring Gray Matter Concentration Loss across the Huntington Disease Prodrome
Huntington disease (HD) is caused by an abnormally expanded cytosine–adenine–guanine (CAG) trinucleotide repeat in the HTT gene. Age and CAG-expansion number are related to age at diagnosis and can be used to index disease progression. However, observed onset-age variability suggests that other fact...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030293/ https://www.ncbi.nlm.nih.gov/pubmed/27708610 http://dx.doi.org/10.3389/fneur.2016.00147 |