Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro

This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing...

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Autores principales: Chatterjee, Sumantra, Kraus, Petra, Sivakamasundari, V., Yap, Sook Peng, Kumar, Vibhor, Prabhakar, Shyam, Lufkin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030313/
https://www.ncbi.nlm.nih.gov/pubmed/27672560
http://dx.doi.org/10.1016/j.gdata.2016.09.002
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author Chatterjee, Sumantra
Kraus, Petra
Sivakamasundari, V.
Yap, Sook Peng
Kumar, Vibhor
Prabhakar, Shyam
Lufkin, Thomas
author_facet Chatterjee, Sumantra
Kraus, Petra
Sivakamasundari, V.
Yap, Sook Peng
Kumar, Vibhor
Prabhakar, Shyam
Lufkin, Thomas
author_sort Chatterjee, Sumantra
collection PubMed
description This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue.
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spelling pubmed-50303132016-09-26 Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro Chatterjee, Sumantra Kraus, Petra Sivakamasundari, V. Yap, Sook Peng Kumar, Vibhor Prabhakar, Shyam Lufkin, Thomas Genom Data Data in Brief This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue. Elsevier 2016-09-08 /pmc/articles/PMC5030313/ /pubmed/27672560 http://dx.doi.org/10.1016/j.gdata.2016.09.002 Text en © 2016 Stellenbosch University http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data in Brief
Chatterjee, Sumantra
Kraus, Petra
Sivakamasundari, V.
Yap, Sook Peng
Kumar, Vibhor
Prabhakar, Shyam
Lufkin, Thomas
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_full Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_fullStr Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_full_unstemmed Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_short Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_sort genome wide binding (chip-seq) of murine bapx1 and sox9 proteins in vivo and in vitro
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030313/
https://www.ncbi.nlm.nih.gov/pubmed/27672560
http://dx.doi.org/10.1016/j.gdata.2016.09.002
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