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Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation

SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or B...

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Detalles Bibliográficos
Autores principales: van der Knijff-van Dortmont, A. L. M. J., Dirckx, M., Duvekot, J. J., Roos-Hesselink, J. W., Gonzalez Candel, A., van der Marel, C. D., Scoones, G. P., Adriaens, V. F. R., Dons-Sinke, I. J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030394/
https://www.ncbi.nlm.nih.gov/pubmed/27668095
http://dx.doi.org/10.1155/2016/9278409
Descripción
Sumario:SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.