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Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or B...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030394/ https://www.ncbi.nlm.nih.gov/pubmed/27668095 http://dx.doi.org/10.1155/2016/9278409 |
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author | van der Knijff-van Dortmont, A. L. M. J. Dirckx, M. Duvekot, J. J. Roos-Hesselink, J. W. Gonzalez Candel, A. van der Marel, C. D. Scoones, G. P. Adriaens, V. F. R. Dons-Sinke, I. J. J. |
author_facet | van der Knijff-van Dortmont, A. L. M. J. Dirckx, M. Duvekot, J. J. Roos-Hesselink, J. W. Gonzalez Candel, A. van der Marel, C. D. Scoones, G. P. Adriaens, V. F. R. Dons-Sinke, I. J. J. |
author_sort | van der Knijff-van Dortmont, A. L. M. J. |
collection | PubMed |
description | SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour. |
format | Online Article Text |
id | pubmed-5030394 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-50303942016-09-25 Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation van der Knijff-van Dortmont, A. L. M. J. Dirckx, M. Duvekot, J. J. Roos-Hesselink, J. W. Gonzalez Candel, A. van der Marel, C. D. Scoones, G. P. Adriaens, V. F. R. Dons-Sinke, I. J. J. Case Rep Anesthesiol Case Report SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour. Hindawi Publishing Corporation 2016 2016-09-07 /pmc/articles/PMC5030394/ /pubmed/27668095 http://dx.doi.org/10.1155/2016/9278409 Text en Copyright © 2016 A. L. M. J. van der Knijff-van Dortmont et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report van der Knijff-van Dortmont, A. L. M. J. Dirckx, M. Duvekot, J. J. Roos-Hesselink, J. W. Gonzalez Candel, A. van der Marel, C. D. Scoones, G. P. Adriaens, V. F. R. Dons-Sinke, I. J. J. Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title | Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title_full | Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title_fullStr | Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title_full_unstemmed | Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title_short | Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation |
title_sort | epidural analgesia with ropivacaine during labour in a patient with a scn5a gene mutation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030394/ https://www.ncbi.nlm.nih.gov/pubmed/27668095 http://dx.doi.org/10.1155/2016/9278409 |
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