Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective

Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystems, especially in cardiovascular, its pharmacological action, clinical app...

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Detalles Bibliográficos
Autores principales: Zhao, Yingke, Liu, Yue, Chen, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030435/
https://www.ncbi.nlm.nih.gov/pubmed/27668034
http://dx.doi.org/10.1155/2016/2124638
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author Zhao, Yingke
Liu, Yue
Chen, Keji
author_facet Zhao, Yingke
Liu, Yue
Chen, Keji
author_sort Zhao, Yingke
collection PubMed
description Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystems, especially in cardiovascular, its pharmacological action, clinical application, and the structural modification have attracted broad attention. In this paper its mechanisms of action, the clinical status, and synthetic derivatives will be reviewed briefly.
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spelling pubmed-50304352016-09-25 Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective Zhao, Yingke Liu, Yue Chen, Keji Oxid Med Cell Longev Review Article Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystems, especially in cardiovascular, its pharmacological action, clinical application, and the structural modification have attracted broad attention. In this paper its mechanisms of action, the clinical status, and synthetic derivatives will be reviewed briefly. Hindawi Publishing Corporation 2016 2016-09-07 /pmc/articles/PMC5030435/ /pubmed/27668034 http://dx.doi.org/10.1155/2016/2124638 Text en Copyright © 2016 Yingke Zhao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhao, Yingke
Liu, Yue
Chen, Keji
Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title_full Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title_fullStr Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title_full_unstemmed Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title_short Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective
title_sort mechanisms and clinical application of tetramethylpyrazine (an interesting natural compound isolated from ligusticum wallichii): current status and perspective
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030435/
https://www.ncbi.nlm.nih.gov/pubmed/27668034
http://dx.doi.org/10.1155/2016/2124638
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AT chenkeji mechanismsandclinicalapplicationoftetramethylpyrazineaninterestingnaturalcompoundisolatedfromligusticumwallichiicurrentstatusandperspective

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