During acute experimental infection with the reticulotropic Trypanosoma cruzi strain Tulahuen IL-22 is induced IL-23-dependently but is dispensable for protection

Protective immunity against Trypanosoma cruzi, the causative agent of Chagas disease, depends on the activation of macrophages by IFN-γ and IL-17A. In contrast, IL-10 prevents immunopathology. IL-22 belongs to the IL-10 cytokine family and has pleiotropic effects during host defense and immunopathol...

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Detalles Bibliográficos
Autores principales: Erdmann, Hanna, Behrends, Jochen, Hölscher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030675/
https://www.ncbi.nlm.nih.gov/pubmed/27650379
http://dx.doi.org/10.1038/srep32927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030675/
https://www.ncbi.nlm.nih.gov/pubmed/27650379
http://dx.doi.org/10.1038/srep32927

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