Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures

The application of patient-derived three-dimensional culture systems as disease-specific drug sensitivity models has enormous potential to connect compound screening and clinical trials. However, the implementation of complex cell-based assay systems in drug discovery requires reliable and robust sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Boehnke, Karsten, Iversen, Philip W., Schumacher, Dirk, Lallena, María José, Haro, Rubén, Amat, Joaquín, Haybaeck, Johannes, Liebs, Sandra, Lange, Martin, Schäfer, Reinhold, Regenbrecht, Christian R. A., Reinhard, Christoph, Velasco, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030729/
https://www.ncbi.nlm.nih.gov/pubmed/27233291
http://dx.doi.org/10.1177/1087057116650965

Ejemplares similares

Ejemplares similares