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The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells
Pentraxin 3 (PTX3) is a fluid-phase pattern recognition receptor of the humoral innate immune system with ancestral antibody-like properties but unknown antibody-inducing function. In this study, we found binding of PTX3 to splenic marginal zone (MZ) B cells, an innate-like subset of antibody-produc...
Autores principales: | Chorny, Alejo, Casas-Recasens, Sandra, Sintes, Jordi, Shan, Meimei, Polentarutti, Nadia, García-Escudero, Ramón, Walland, A. Cooper, Yeiser, John R., Cassis, Linda, Carrillo, Jorge, Puga, Irene, Cunha, Cristina, Bastos, Hélder, Rodrigues, Fernando, Lacerda, João F., Morais, António, Dieguez-Gonzalez, Rebeca, Heeger, Peter S., Salvatori, Giovanni, Carvalho, Agostinho, Garcia-Sastre, Adolfo, Blander, J. Magarian, Mantovani, Alberto, Garlanda, Cecilia, Cerutti, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030794/ https://www.ncbi.nlm.nih.gov/pubmed/27621420 http://dx.doi.org/10.1084/jem.20150282 |
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