Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4

During homeostasis, hematopoietic stem cells (HSCs) are mostly kept in quiescence with only minor contribution to steady-state hematopoiesis. However, in stress situations such as infection, chemotherapy, or transplantation, HSCs are forced to proliferate and rapidly regenerate compromised hematopoi...

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Detalles Bibliográficos
Autores principales: Uckelmann, Hannah, Blaszkiewicz, Sandra, Nicolae, Claudia, Haas, Simon, Schnell, Alexandra, Wurzer, Stephan, Wagener, Raimund, Aszodi, Attila, Essers, Marieke Alida Gertruda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030798/
https://www.ncbi.nlm.nih.gov/pubmed/27573814
http://dx.doi.org/10.1084/jem.20151713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030798/
https://www.ncbi.nlm.nih.gov/pubmed/27573814
http://dx.doi.org/10.1084/jem.20151713

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