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Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4
During homeostasis, hematopoietic stem cells (HSCs) are mostly kept in quiescence with only minor contribution to steady-state hematopoiesis. However, in stress situations such as infection, chemotherapy, or transplantation, HSCs are forced to proliferate and rapidly regenerate compromised hematopoi...
Autores principales: | Uckelmann, Hannah, Blaszkiewicz, Sandra, Nicolae, Claudia, Haas, Simon, Schnell, Alexandra, Wurzer, Stephan, Wagener, Raimund, Aszodi, Attila, Essers, Marieke Alida Gertruda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030798/ https://www.ncbi.nlm.nih.gov/pubmed/27573814 http://dx.doi.org/10.1084/jem.20151713 |
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