Cargando…

Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice

Both animal model and human studies indicate that commensal bacteria may modify type 1 diabetes (T1D) development. However, the underlying mechanisms by which gut microbes could trigger or protect from diabetes are not fully understood, especially the interaction of commensal bacteria with pathogeni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tai, Ningwen, Peng, Jian, Liu, Fuqiang, Gulden, Elke, Hu, Youjia, Zhang, Xiaojun, Chen, Li, Wong, F. Susan, Wen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030808/ https://www.ncbi.nlm.nih.gov/pubmed/27621416 http://dx.doi.org/10.1084/jem.20160526

Ejemplares similares

NLRP6 deficiency expands a novel CD103(+) B cell population that confers immune tolerance in NOD mice
por: Pearson, James A., et al.
Publicado: (2023)

Prevention of “Humanized” Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach
por: Niens, Marijke, et al.
Publicado: (2011)

Idd9/11 Genetic Locus Regulates Diabetogenic Activity of CD4 T-Cells in Nonobese Diabetic (NOD) Mice
por: Chen, Yi-Guang, et al.
Publicado: (2008)

Islet Amyloid Polypeptide Is a Target Antigen for Diabetogenic CD4(+) T Cells
por: Delong, Thomas, et al.
Publicado: (2011)

IL-10 Deficiency Accelerates Type 1 Diabetes Development via Modulation of Innate and Adaptive Immune Cells and Gut Microbiota in BDC2.5 NOD Mice
por: Huang, Juan, et al.
Publicado: (2021)

Insulin-Reactive T Cells Convert Diabetogenic Insulin-Reactive VH125 B Cells Into Tolerogenic Cells by Reducing Germinal Center T:B Cell Interactions in NOD Mice
por: Pearson, James A., et al.
Publicado: (2020)

Diabetogene Umweltfaktoren
por: Wabnitz, Katharina, et al.
Publicado: (2022)

Efficient Presentation of Multiple Endogenous Epitopes to Both CD4(+) and CD8(+) Diabetogenic T Cells for Tolerance
por: Dastagir, Shamael R., et al.
Publicado: (2016)

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process
Publicado: (1994)

CD4(+) T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8(+) T Cell Function in the Pancreas
por: Espinosa-Carrasco, Gabriel, et al.
Publicado: (2018)

Evaluation of different mucosal microbiota leads to gut microbiota-based prediction of type 1 diabetes in NOD mice
por: Hu, Youjia, et al.
Publicado: (2018)

Statin diabetogenicity: guidance for clinicians
por: Ray, Kausik
Publicado: (2013)

In Vivo Enrichment of Diabetogenic T Cells
por: Thelin, Martin A., et al.
Publicado: (2017)

Epigenetic regulation of diabetogenic adipose morphology
por: Kerr, A.G., et al.
Publicado: (2019)

Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation
por: Reed, Brendan, et al.
Publicado: (2020)

Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes
por: Reed, Brendan K., et al.
Publicado: (2021)

Diabetogenic Potential of Ancestral and Modern Wheat Landraces
por: Aguayo-Patrón, Sandra V., et al.
Publicado: (2017)

Diabetogenic Effects of Ochratoxin A in Female Rats
por: Mor, Firdevs, et al.
Publicado: (2017)

Long-Term Remission of Diabetes in NOD Mice Is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies
por: Yi, Zuoan, et al.
Publicado: (2012)

Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice
por: Lorza-Gil, Estela, et al.
Publicado: (2019)

IRAK-M Deficiency Promotes the Development of Type 1 Diabetes in NOD Mice
por: Tan, Qiyuan, et al.
Publicado: (2014)

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
Publicado: (1996)

COMPARATIVE DIABETOGENIC ACTION OF THE HYPOPHYSIS FROM VARIOUS ANIMALS
por: Houssay, B. A., et al.
Publicado: (1942)

Diabetogenic Effect of Statins: A Double-Edged Sword?
por: Yoon, Ji Sung, et al.
Publicado: (2013)

Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo
por: Cho, Yongin, et al.
Publicado: (2020)

Brève : Sars-CoV-2, agent diabétogène ?
por: Dalmat, Yann-Mickael
Publicado: (2021)

T Cell Intrinsic NOD2 Is Dispensable for CD8 T Cell Immunity
por: Lin, Gloria H. Y., et al.
Publicado: (2013)

Cyclic AMP and calcium signaling are involved in antipsychotic-induced diabetogenic effects in isolated pancreatic β cells of CD1 mice
por: Al-Ghafari, Ayat, et al.
Publicado: (2022)

Fat feeding potentiates the diabetogenic effect of dexamethasone in Wistar rats
por: Sivabalan, Shanmugam, et al.
Publicado: (2008)

Diabetogenic T-Cell Clones Recognize an Altered Peptide of Chromogranin A
por: Delong, Thomas, et al.
Publicado: (2012)

Population attributable risks and costs of diabetogenic chemical exposures in the elderly
por: Trasande, Leonardo, et al.
Publicado: (2017)

Diabetogenically beneficial gut microbiota alterations in third trimester of pregnancy
por: Amabebe, Emmanuel, et al.
Publicado: (2021)

Endocrine disruptor chemicals as obesogen and diabetogen: Clinical and mechanistic evidence
por: Kurşunoğlu, Niyazi Emre, et al.
Publicado: (2022)

Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions
por: Pearson, James A., et al.
Publicado: (2019)

Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes
por: Padgett, Lindsey E., et al.
Publicado: (2015)

Slc11a1 Enhances the Autoimmune Diabetogenic T-Cell Response by Altering Processing and Presentation of Pancreatic Islet Antigens
por: Dai, Yang D., et al.
Publicado: (2009)

Evaluation of Diabetogenic Mechanism of High Fat Diet in Combination with Arsenic Exposure in Male Mice
por: Ahangarpour, Akram, et al.
Publicado: (2018)

Epigenetic effects of in utero bisphenol A administration: Diabetogenic and atherogenic changes in mice offspring
por: Bano, Umbreen, et al.
Publicado: (2019)

Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage
por: Kasmani, Moujtaba Y, et al.
Publicado: (2022)

Strain-Dependent Migration of CD4 and CD8 Lymphocyte Subsets to Lymph Nodes in NOD (Nonobese Diabetic) and Control Mice
por: Faveeuw, Christelle, et al.
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_g385j1tq8qcofe34ju01e8abru