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Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL‐17 responses

The Th17/IL‐17 pathway is implicated in the pathogenesis of periodontitis (PD), however the mechanisms are not fully understood. We investigated the mechanism by which the periodontal pathogens Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) promote a Th17/IL‐17 response...

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Detalles Bibliográficos
Autores principales: Cheng, Wan‐Chien, van Asten, Saskia D., Burns, Lachrissa A., Evans, Hayley G., Walter, Gina J., Hashim, Ahmed, Hughes, Francis J., Taams, Leonie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031191/
https://www.ncbi.nlm.nih.gov/pubmed/27334899
http://dx.doi.org/10.1002/eji.201545871