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P53 and the defenses against genome instability caused by transposons and repetitive elements

The recent publication by Wylie et al. is reviewed, demonstrating that the p53 protein regulates the movement of transposons. While this work presents genetic evidence for a piRNA‐mediated p53 interaction with transposons in Drosophila and zebrafish, it is herein placed in the context of a decade or...

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Detalles Bibliográficos
Autores principales: Levine, Arnold J., Ting, David T., Greenbaum, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031199/
https://www.ncbi.nlm.nih.gov/pubmed/27172878
http://dx.doi.org/10.1002/bies.201600031