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Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways

BACKGROUND: Bicyclol, a novel synthetic antihepatitis drug, is widely known to protect against liver injury. However, few reports have focused on the possible effect of bicyclol on anti-proliferation and autophagy induction in cancer cells, particularly hepatocellular carcinoma cells. METHODS: In th...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Nie, Hao, Zhao, Xin, Qin, Yong, Gong, Xingguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031284/ https://www.ncbi.nlm.nih.gov/pubmed/27654866 http://dx.doi.org/10.1186/s12885-016-2767-2

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