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Interferon-γ blocks signalling through PDGFRβ in human brain pericytes

BACKGROUND: Neuroinflammation and blood-brain barrier (BBB) disruption are common features of many brain disorders, including Alzheimer’s disease, epilepsy, and motor neuron disease. Inflammation is thought to be a driver of BBB breakdown, but the underlying mechanisms for this are unclear. Brain pe...

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Detalles Bibliográficos
Autores principales:	Jansson, Deidre, Scotter, Emma L., Rustenhoven, Justin, Coppieters, Natacha, Smyth, Leon C. D., Oldfield, Robyn L., Bergin, Peter S., Mee, Edward W., Graham, E. Scott, Faull, Richard L. M., Dragunow, Mike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031293/ https://www.ncbi.nlm.nih.gov/pubmed/27654972 http://dx.doi.org/10.1186/s12974-016-0722-4

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