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Structure of the catalytic domain of the colistin resistance enzyme MCR-1

BACKGROUND: Due to the paucity of novel antibiotics, colistin has become a last resort antibiotic for treating multidrug resistant bacteria. Colistin acts by binding the lipid A component of lipopolysaccharides and subsequently disrupting the bacterial membrane. The recently identified plasmid-encod...

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Detalles Bibliográficos
Autores principales:	Stojanoski, Vlatko, Sankaran, Banumathi, Prasad, B. V. Venkataram, Poirel, Laurent, Nordmann, Patrice, Palzkill, Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031297/ https://www.ncbi.nlm.nih.gov/pubmed/27655155 http://dx.doi.org/10.1186/s12915-016-0303-0

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