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Prolonged persistence of a novel replication-defective HIV-1 variant in plasma of a patient on suppressive therapy
BACKGROUND: Cell-free residual HIV-1 virions (RVs) persist in plasma below 20–50 vRNA copies/ml in most patients on suppressive antiretroviral therapy (ART). How RVs are produced in the body during therapy is not fully clear. In this study, we have attempted to characterize these viruses of an ART-t...
Autores principales: | Rassler, Samantha, Ramirez, Roberto, Khoury, Nadeen, Skowron, Gail, Sahu, Gautam K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031319/ https://www.ncbi.nlm.nih.gov/pubmed/27655142 http://dx.doi.org/10.1186/s12985-016-0617-0 |
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