Lapatinib-capecitabine versus capecitabine alone as radiosensitizers in RAS wild-type resectable rectal cancer, an adaptive randomized phase II trial (LaRRC trial): study protocol for a randomized controlled trial

BACKGROUND: Preoperative radiochemotherapy followed by surgical removal of the rectum with total mesorectum excision is the preferred treatment option for stages II and III rectal cancer. However, development of metastatic disease is the main cause of death for these patients with 5-year disease-fre...

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Detalles Bibliográficos
Autores principales: Sousa, Nuno, Sousa, Olga, Santos, Lúcio Lara, Henrique, Rui, Teixeira, Manuel R., Dinis-Ribeiro, Mário, Teixeira-Pinto, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031350/
https://www.ncbi.nlm.nih.gov/pubmed/27655166
http://dx.doi.org/10.1186/s13063-016-1583-y

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