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Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?

Several recent studies have investigated either genetic or epigenetic variation in schizophrenia. A recent study presents comprehensive analyses of blood samples to better characterize the combined role of genetic and epigenetic variation in schizophrenia. While the paper identifies significant asso...

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Detalles Bibliográficos
Autores principales: Jaffe, Andrew E., Kleinman, Joel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031351/
https://www.ncbi.nlm.nih.gov/pubmed/27655387
http://dx.doi.org/10.1186/s13073-016-0354-4
Descripción
Sumario:Several recent studies have investigated either genetic or epigenetic variation in schizophrenia. A recent study presents comprehensive analyses of blood samples to better characterize the combined role of genetic and epigenetic variation in schizophrenia. While the paper identifies significant associations with schizophrenia risk and diagnosis, the potential relevance to the brain in schizophrenia is questionable.