Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?

Several recent studies have investigated either genetic or epigenetic variation in schizophrenia. A recent study presents comprehensive analyses of blood samples to better characterize the combined role of genetic and epigenetic variation in schizophrenia. While the paper identifies significant asso...

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Detalles Bibliográficos
Autores principales: Jaffe, Andrew E., Kleinman, Joel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031351/
https://www.ncbi.nlm.nih.gov/pubmed/27655387
http://dx.doi.org/10.1186/s13073-016-0354-4
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author Jaffe, Andrew E.
Kleinman, Joel E.
author_facet Jaffe, Andrew E.
Kleinman, Joel E.
author_sort Jaffe, Andrew E.
collection PubMed
description Several recent studies have investigated either genetic or epigenetic variation in schizophrenia. A recent study presents comprehensive analyses of blood samples to better characterize the combined role of genetic and epigenetic variation in schizophrenia. While the paper identifies significant associations with schizophrenia risk and diagnosis, the potential relevance to the brain in schizophrenia is questionable.
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spelling pubmed-50313512016-09-29 Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer? Jaffe, Andrew E. Kleinman, Joel E. Genome Med Comment Several recent studies have investigated either genetic or epigenetic variation in schizophrenia. A recent study presents comprehensive analyses of blood samples to better characterize the combined role of genetic and epigenetic variation in schizophrenia. While the paper identifies significant associations with schizophrenia risk and diagnosis, the potential relevance to the brain in schizophrenia is questionable. BioMed Central 2016-09-21 /pmc/articles/PMC5031351/ /pubmed/27655387 http://dx.doi.org/10.1186/s13073-016-0354-4 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Jaffe, Andrew E.
Kleinman, Joel E.
Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title_full Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title_fullStr Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title_full_unstemmed Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title_short Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
title_sort genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031351/
https://www.ncbi.nlm.nih.gov/pubmed/27655387
http://dx.doi.org/10.1186/s13073-016-0354-4
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