The Mouse-Specific Splice Variant mRAGE_v4 Encodes a Membrane-Bound RAGE That Is Resistant to Shedding and Does Not Contribute to the Production of Soluble RAGE

The receptor for advanced glycation end-products (RAGE) is involved in the onset and progression of several inflammatory diseases. The RAGE primary transcript undergoes numerous alternative splicing (AS) events, some of which are species-specific. Here, we characterize the mouse-specific mRAGE_v4 sp...

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Detalles Bibliográficos
Autores principales: Di Maggio, Stefania, Gatti, Elena, Liu, Jaron, Bertolotti, Matteo, Fritz, Günter, Bianchi, Marco E., Raucci, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031469/
https://www.ncbi.nlm.nih.gov/pubmed/27655137
http://dx.doi.org/10.1371/journal.pone.0153832

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